Investigators: Henry Brodaty (CI), Megan Heffernen, Perminder Sachdev, John McNeil, Anthony Maeder, Nicola Lautenschlager, Louisa Jorm, Maria Fiatarone Singh, Kaarin Anstey, Gavin Andrews Maintain Your Brain (MYB) is a randomised controlled trial of multiple online interventions designed to target modifiable risk factors for Alzheimer’s disease and deme. Risk factors to be addressed are physical inactivity, cognitive inactivity, depression, overweight and obesity, and poor diet. Four intervention modules (physical activity and nutrition, cognitive training and depression) will be customised to individual risk profiles. Each module will be initially delivered using MYB eHealth platform over three months. In the active intervention phase participants complete all four modules is 12 months. Booster sessions and monitoring will continue for four years. Follow-up assessments measuring these risk factors and cognition will be completed annually for four years. The comparison control group will receive basic psychoeducation online about dementia risk factors and otherwise receive usual care and undertake the same set of assessments.