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This Evidence Check review examines models of managing nicotine dependence in health facilities under a smoke-free healthcare policy directive. The research evidence suggests that smoking cessation can be increased via a number of interventions including: smoking status assessment; provision of advice/counselling; nicotine replacement therapy; and referral for specialist follow-up. A number of clinical practice strategies, such as training, electronic reminders and leadership were found to be effective at increasing clinician provision of smoking cessation care. A review of best practice documents and initiatives implemented in Australasian jurisdictions identified a number of policies, frameworks, tools and services intended to support delivery of smoking cessation care.